The SNX13 Antibody (C-term) from MyBioSource.com is a Rabbit Polyclonal antibody to SNX13. This antibody recognizes Human antigen. The SNX13 Antibody (C-term) has been validated for the following applications: ELISA, and Western Blot.
Description
This gene encodes a PHOX domain- and RGS domain-containing
protein that belongs to the sorting nexin (SNX) family and the
regulator of G protein signaling (RGS) family. The PHOX domain is a
phosphoinositide binding domain, and the SNX family members are
involved in intracellular trafficking. The RGS family members are
regulatory molecules that act as GTPase activating proteins for G
alpha subunits of heterotrimeric G proteins. The RGS domain of this
protein interacts with G alpha(s), accelerates its GTP hydrolysis,
and attenuates G alpha(s)-mediated signaling. Overexpression of
this protein delayes lysosomal degradation of the epidermal growth
factor receptor. Because of its bifunctional role, this protein may
link heterotrimeric G protein signaling and vesicular trafficking